Comments on: An unusual cause of jaundice… (or is it?) http://medicaleducator.co.uk/an-unusual-cause-of-jaundice-or-is-it.html Medical students - get help passing and revise for your medical student exams with our multi choice questions (MCQs/EMQs), videos, podcasts and downloads. Free resources give it a trial! Mon, 30 Jan 2012 19:10:04 +0000 hourly 1 http://wordpress.org/?v= By: James http://medicaleducator.co.uk/an-unusual-cause-of-jaundice-or-is-it.html/comment-page-1#comment-1055 James Mon, 11 May 2009 16:17:54 +0000 http://medicaleducator.co.uk/blog/?p=113#comment-1055 Thanks Mike, it is a bit of an unfair one this! We thought we'd let people debate it for a while. Hepatitis B and C can both be reactivated, in this case its most likely dormant hepatitis B. To quote the review from Nature "HBV reactivation is common in patients who receive chemotherapy, immunosuppressive therapy, or other cytotoxic agents. Prophylaxis for HBV reactivation with lamivudine has shown promising efficacy, however, when prophylaxis should be given, to whom and for how long is unclear." Essentially the bottom line is you need to start antivirals in this population prior to getting Hep B, and continue them for at least 12 months. Read more at the following link: http://www.nature.com/nrgastro/journal/v4/n3/full/ncpgasthep0740.html Thanks Mike, it is a bit of an unfair one this! We thought we’d let people debate it for a while. Hepatitis B and C can both be reactivated, in this case its most likely dormant hepatitis B. To quote the review from Nature

“HBV reactivation is common in patients who receive chemotherapy, immunosuppressive therapy, or other cytotoxic agents. Prophylaxis for HBV reactivation with lamivudine has shown promising efficacy, however, when prophylaxis should be given, to whom and for how long is unclear.”

Essentially the bottom line is you need to start antivirals in this population prior to getting Hep B, and continue them for at least 12 months.

Read more at the following link:
http://www.nature.com/nrgastro/journal/v4/n3/full/ncpgasthep0740.html

]]> By: mike http://medicaleducator.co.uk/an-unusual-cause-of-jaundice-or-is-it.html/comment-page-1#comment-1046 mike Wed, 29 Apr 2009 10:01:46 +0000 http://medicaleducator.co.uk/blog/?p=113#comment-1046 anthracycline chemotherapy based toxicity anthracycline chemotherapy based toxicity

]]> By: Star1 http://medicaleducator.co.uk/an-unusual-cause-of-jaundice-or-is-it.html/comment-page-1#comment-82 Star1 Sun, 23 Nov 2008 23:54:22 +0000 http://medicaleducator.co.uk/blog/?p=113#comment-82 agree with above management. pcr for hepatitis virus agree with above management. pcr for hepatitis virus

]]> By: France http://medicaleducator.co.uk/an-unusual-cause-of-jaundice-or-is-it.html/comment-page-1#comment-77 France Tue, 18 Nov 2008 20:06:49 +0000 http://medicaleducator.co.uk/blog/?p=113#comment-77 this is a 'hepatitic' picture with not obstructive could still be a viral hepatitis if they have had chemo and they are immunosupressed this most likely if no other cause found check hepatitis b and hepatitis c serology and liver consult this is a ‘hepatitic’ picture with not obstructive

could still be a viral hepatitis if they have had chemo and they are immunosupressed

this most likely if no other cause found

check hepatitis b and hepatitis c serology and liver consult

]]> By: G Male http://medicaleducator.co.uk/an-unusual-cause-of-jaundice-or-is-it.html/comment-page-1#comment-67 G Male Sun, 16 Nov 2008 22:47:18 +0000 http://medicaleducator.co.uk/blog/?p=113#comment-67 Acute hepatitis Unlikely to be a viral hepatitis Lymphatic obstruction seems to be logical but it doesn't fit with the LFT's That Looks hepatitic rather than obstructive... G Acute hepatitis
Unlikely to be a viral hepatitis
Lymphatic obstruction seems to be logical but it doesn’t fit with the LFT’s

That Looks hepatitic rather than obstructive…
G

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